COMPAMIR
High-Purity Fact Pipeline
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High-Purity Fact Pipeline
Rohit Loomba (UC San Diego School of Medicine) and Ionis Pharmaceuticals
United States
May 27, 2026
Verified: May 27, 2026
"A Phase IIb clinical trial found that ION224, a drug blocking the DGAT2 enzyme, improves liver health in patients with MASH. Approximately 60% of patients receiving the highest dose showed meaningful improvements. The drug targets the root cause of fat accumulation in the liver."