"Research presented at ENDO 2026 shows that patients taking GLP-1 medications like Ozempic and Wegovy experienced a significant decline in daily steps and moderate-to-vigorous physical activity. The study analyzed data from 753 adults, finding that average daily steps dropped from 5,047 to 4,487. Researchers emphasize that exercise remains essential for maintaining muscle mass during weight loss, as these drugs can contribute to lean muscle loss."